tert-butyl 2-[4-(piperazin-1-yl)piperidin-1-yl]acetate deuterium-labeled-heterocycle Product Name Thalidomide-5'-O-PEG2-C2-acid Synonyms CAS

Product Name Thalidomide-5'-O-PEG2-C2-acid Synonyms CAS Number 2682112-08-7 Related CAS Molecular Formula C20H22N2O9 Molecular Weight 434

Avadomide (CC-122) is an orally active cereblon modulator

562 SMILES OC1=CC2=C(C=C1)C1(OC(=O)C3=CC=C(C=C13)C(=O)NCCOCCOCCOCCN=[N+]=[N-])C1=CC=C(O)C=C1O2 Purity (HPLC) 98% Shipping Conditions Room Temperature Storage Conditions Refrigerated Regulatory Statemen: For Research Use Only

66 SMILES CC1=C(SC=N1)C1=CC=C(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)COCCO)C(C)(C)C)C=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

78 SMILES ClCCCC(=O)NC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

tert-butyl 2-[4-(piperazin-1-yl)piperidin-1-yl]acetate deuterium-labeled-heterocycle Product Name Thalidomide-5'-O-PEG2-C2-acid Synonyms CASNitrogen Heterocycle Based Linker (NHBL). Binfunctional amine carboxylic acid linker. Product Name tert butyl 2 [4 (piperazin 1 yl)piperidin 1 yl]acetate Synonyms 1 Piperidineacetic acid, 4 (1 piperazinyl) , 1,1 dimethylethyl ester CAS Number 149554 09 6 Related CAS Molecular Formula C15H29N3O2 Molecular Weight 283. 416 SMILES CC(C)(C)OC(=O)CN1CCC(CC1)N1CCNCC1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated