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Mal-Propionyl-PEG2-Val-Cit-PAB(m-PEG4) Size:100mg S)-AHPC-CO-PEG4-C2-acid Synonyms CAS Number 2172820-12-9

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Description

S)-AHPC-CO-PEG4-C2-acid Synonyms CAS Number 2172820-12-9 Related CAS Molecular Formula C34H50N4O10S Molecular Weight 706

Product Name Phthalimidinoglutarimide-C5-amine HCl Synonyms Phthalimidinoglutarimide-4'-C5-amine HCl CAS Number 2093388-45-3 Related CAS Molecular Formula C18H24ClN3O3 Molecular Weight 365

Nishiguchi

405 SMILES [N-]=[N+]=NCCCCNC(=O)COC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

213 Purity (HPLC) >= 95% Solubility DMSO

Mal-Propionyl-PEG2-Val-Cit-PAB(m-PEG4) Size:100mg S)-AHPC-CO-PEG4-C2-acid Synonyms CAS Number 2172820-12-9SOLU KNEX cleavable linker features a Val Cit dipeptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG2 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. Derived from established ADC linker architectures, SOLU KNEX

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